Joe Allen out of Wales v Czech Republic World Cup qualifier

Allen, 31, limped off only seven minutes into the match against Group E favourites Belgium on Wednesday -- a miserable return to international action for the influential player.

Allen, who had not played for Wales since 2019 after suffering an Achilles injury, was one of their star performers as they reached the Euro 2016 semi-finals.

"We've lost Joe, which is a shame," said Page. "It is a big loss for us. It's disappointing not to have him. He'll have to go back to the club (Stoke) now and they'll assess him."

Wales play a Cardiff friendly against Mexico on Saturday while the Czechs, 6-2 winners away to Estonia in their opening qualifier, are at home to Belgium. Wales host the Czechs on Tuesday.

Only the group winners progress automatically to the finals in Qatar in 2022.

Page will also be without defenders Ben Davies, Tom Lockyer and James Lawrence for the next two games.

Charlton full-back Chris Gunter will lead the side out against Mexico, becoming the first Welshman to win 100 caps.

"He's a model professional and thoroughly deserves 100 caps and all the credit he will get for having achieved that," said Page.

"It's good to be a part of that with him. He's a good lad, certainly one of the people you want to see in the game do well."