Champions League last-16 second leg: What's cooking in Wednesday's fixtures?

The first-leg results have set the stage for decisive encounters. Some teams will look to capitalise on their advantage, while others will attempt to overturn deficits in pursuit of European glory.

Lille vs Borussia Dortmund

Lille and Borussia Dortmund remain deadlocked after a closely contested 1-1 draw in Germany. With everything to play for, the French side will be determined to make the most of home advantage in front of their passionate fans. Bruno Genesio's men have been resolute defensively, and they will need to maintain their composure to contain Dortmund's attacking threats.

Dortmund, on the other hand, have struggled for consistency in the Bundesliga but will hope their European pedigree sees them through. Niko Kovac's side must produce a composed performance on French soil to book their place in the quarter-finals.

Awaiting the winners in the next round is Barcelona, who have already secured their place in the quarter-finals.

Aston Villa vs Club Brugge

Aston Villa return to Villa Park with a commanding 3-1 lead from the first leg in Belgium. Unai Emery's side displayed their attacking prowess in Brugge and will now look to finish the job in front of their home supporters. Villa's impressive European campaign so far has seen them emerge as serious contenders, and with a two-goal cushion, they will be confident of progressing.

However, Club Brugge are not out of the tie just yet. The Belgian outfit has already caused surprises in this season's competition and will aim to stage a dramatic comeback. A fast start will be crucial if they are to stand any chance of unsettling their Premier League opposition.

The winners of this tie will face Paris Saint-Germain in the quarter-finals, after the French side eliminated Arne Slot's Liverpool on Tuesday.

Atletico Madrid vs Real Madrid

The Madrid derby takes centre stage once again as Atletico Madrid seek to overturn a 2-1 deficit at the Metropolitano. Diego Simeone's men will take confidence from playing on home turf, knowing that a single goal could change the entire complexion of the tie. Their defensive discipline will be key, but they will also need to take their chances against their city rivals.

Real Madrid, meanwhile, are on the hunt for yet another Champions League crown. Carlo Ancelotti's side has the advantage but will be wary of Atletico's ability to thrive in high-pressure situations. With Vinicius Jr, Jude Bellingham and Rodrygo in top form, Los Blancos will look to finish off the tie and keep their European dream alive.

The winners of this thrilling tie will go on to face either Arsenal or PSV in the quarter-finals.

Arsenal vs PSV Eindhoven

Arsenal have one foot firmly in the quarter-finals after an emphatic 7-1 demolition of PSV in the first leg. Mikel Arteta's side delivered a statement performance in Eindhoven, leaving their Dutch opponents with a near-impossible task in London. The Gunners will likely rotate their squad, given their comfortable lead, but will still want to put on a professional display for their home fans.

For PSV, the second leg is about salvaging pride. After a humbling first-leg defeat, they will be looking for a much-improved performance at the Emirates Stadium. While a comeback is highly improbable, they will hope to at least restore some dignity in their final European outing of the season.

With the stakes at their highest, the Champions League drama is set to continue as teams battle for their place in the quarter-finals. Meanwhile, the last quarter-final tie is already set, with Bayern Munich set to face Inter Milan.